Psychedelic Science & Therapy
Evidence-based psychedelic research, clinical trials, therapeutic protocols, and integration practices
117 resources
Food of the Gods: The Search for the Original Tree of Knowledge
Terence McKenna
McKenna's exploration of the evolutionary relationship between humans and psychoactive plants, proposing the 'Stoned Ape' theory that psilocybin mushrooms influenced human consciousness development.
The Archaic Revival
Terence McKenna
Essays and interviews exploring psychedelic mushrooms, virtual reality, UFOs, shamanism, and the rebirth of the Goddess. Features a foreword by Tom Robbins.
Dennis McKenna on Joe Rogan Experience
Terence McKenna
Episodes featuring Terence's brother Dennis McKenna discussing psychedelics, ethnobotany, and Terence's legacy. Includes episodes #946 and #1133.
Mycelium Running: How Mushrooms Can Help Save the World
Paul Stamets
Comprehensive guide to using fungi for environmental restoration through mycoremediation, mycofiltration, and mycopesticides. Features over 500 photographs and detailed cultivation techniques.
Fantastic Fungi: How Mushrooms Can Heal, Shift Consciousness, and Save the Planet
Paul Stamets
Companion book to the documentary, edited by Paul Stamets with contributions from Michael Pollan, Andrew Weil, and others exploring the potential of fungi.
Joe Rogan Experience #1035 - Paul Stamets
Paul Stamets
First of multiple JRE appearances discussing fungi, consciousness, and the healing potential of mushrooms. 2+ hours of in-depth conversation.
6 Ways Mushrooms Can Save the World - TED Talk
Paul Stamets
Stamets' famous 2008 TED Talk with over 6 million views, exploring how mycelium can clean polluted soil, develop insecticides, and potentially treat diseases.
Paul Stamets at TEDMED 2011
Paul Stamets
TEDMED presentation focusing on the antimicrobial properties of fungi, their efficacy as insecticides, and potential to boost the human immune system.
The Ketamine Papers: Science, Therapy, and Transformation
Phil Wolfson & Glenn Hartelius
Comprehensive examination of ketamine's therapeutic applications, covering science, clinical protocols, and transformative potential for treating depression and trauma. Published by MAPS (2016).
Ketamine for Depression
Stephen J. Hyde
Clinical guide exploring ketamine's revolutionary role in treating treatment-resistant depression, including sublingual protocols and patient outcomes (2015).
A Manual for MDMA-Assisted Psychotherapy in the Treatment of PTSD
Michael Mithoefer et al.
Official MAPS treatment manual providing detailed clinical protocols for MDMA-assisted psychotherapy in PTSD treatment (Version 7, 2015).
MDMA-Assisted Psychotherapy Code of Ethics
MAPS
Ethical guidelines for practitioners conducting MDMA-assisted psychotherapy, addressing boundaries, safety, and professional standards (2019).
In the Realm of Hungry Ghosts: Close Encounters with Addiction
Gabor Maté
Compassionate exploration of addiction through trauma-informed lens, examining root causes and pathways to healing (2010).
The Healing Journey: New Approaches to Consciousness
Claudio Naranjo
Classic text documenting early psychedelic psychotherapy research with harmaline, ibogaine, and MDA (1974).
Sensorimotor Psychotherapy: Interventions for Trauma and Attachment
Pat Ogden & Janina Fisher
Comprehensive guide to body-based trauma treatment integrating somatic approaches with attachment theory (2015).
Sacred Knowledge: Psychedelics and Religious Experiences
William A. Richards
Exploration of mystical experiences in psychedelic therapy by a pioneering Johns Hopkins researcher (2015).
The Ethics of Caring: Honoring the Web of Life in Our Professional Healing Relationships
Kylea Taylor
Essential ethical framework for practitioners working in consciousness-expanding and holotropic therapy contexts (1995).
The Autistic Psychedelic: Applying Neurodiversity-Affirming Principles to Guide Safe, Meaningful Experiences
Aaron Paul Orsini
Guide for supporting neurodivergent individuals in psychedelic experiences with affirming, safety-focused approaches (2021).
Indigenous psilocybin mushroom practices: An annotated bibliography
Nicholas Speirs et al.
Comprehensive bibliography documenting traditional Indigenous uses of psilocybin mushrooms across cultures.
A Master Key: How Psychedelics May Reopen Critical Periods in the Brain
Greg Rienzi / Johns Hopkins University
Johns Hopkins researchers show that psychedelic drugs including MDMA and psilocybin can reopen critical periods in the brain—windows of enhanced learning and neuroplasticity—potentially enabling treatment for stroke, traumatic brain injury, and other conditions.
Do Psychedelics Increase or Decrease Intelligence?
Dr. Anthony Cave / Medical Secrets
A comprehensive exploration of how psychedelics (ketamine, LSD, psilocybin, MDMA, ayahuasca, mescaline) affect cognitive performance, drawing on clinical experience from over 1,000 IV ketamine sessions and research on neuroplasticity, memory, and creative cognition.
How Ketamine Treats Depression - Yale Medicine Explains
Yale Medicine
Yale Medicine experts explain how ketamine works differently from traditional antidepressants by promoting neuroplasticity and synapse regrowth. Covers the rapid-onset effects, critical periods of brain plasticity, and the importance of combining ketamine with psychotherapy.
IV Ketamine Therapy: Watch A Patient's Transformation from Depression
Dr. Anthony Cave / Medical Secrets
A real patient's documented IV ketamine therapy journey for depression, showing the preparation, infusion experience, and transformative outcomes. Demonstrates responsible clinical ketamine use with integration and follow-up care.
Psychedelic Support
An online directory for finding licensed mental health professionals and integration coaches who specialize in psychedelic-assisted therapy and harm reduction. They also offer online courses and educational resources.
Dr Gabor Maté on Psychedelics, Trauma and The Body (Part 5)
Doctor Explains Psilocybin Therapy
Joe Rogan: The Reason KETAMINE Helps With Depression
War Correspondent Ben Anderson on Receiving Ketamine Therapy | Joe Rogan
Joe Rogan Andrew Huberman talk Ketamine Therapy #shorts
Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
How Ketamine Works & Its Potential for Depression Relief | Dr. Andrew Huberman
Why Dr. Andrew Huberman Changed His Mind About Psychedelics
Ketamine for depression - A Powerful but Tricky Solution
The Psychedelic Revolution – Don’t Forget About Ketamine
Ketamine for Therapy: Inside a Psychedelic Therapy Session
Naturally Healing Trauma with Ketamine Therapy & Psychedelics
From Dead Heads to Depression Meds: How Psychedelics are Impacting Health with Dr. David Olson
What happens to lonely people under psychedelics (ketamine therapy)
Ketamine for Beginners: Mysterious Health Benefits Explained
Ketamine vs. Psychedelics: How Do They Differ?
Psychedelics: effects on the human brain and physiology | Simeon Keremedchiev | TEDxVarna
Psychedelics: Past, present and future | Mark Haden | TEDxEastVan
Ketamine Treatment Q&A | Kyle Kittleson x MedCircle
How can I heal trauma & depression? MDMA & Ketamine are changing therapy
Hopkins Psychedelic — Center for Psychedelic & Consciousness Research
Resource on psychedelics and mental health from hopkinspsychedelic.org
Psychoactive Study — Center for Psychedelic & Consciousness Research
Resource on psychedelics and mental health from hopkinspsychedelic.org
Publications — Center for Psychedelic & Consciousness Research
Resource on psychedelics and mental health from hopkinspsychedelic.org
Student Internships — Center for Psychedelic & Consciousness Research
Resource on psychedelics and mental health from hopkinspsychedelic.org
Keith + Will's Personal Experiences with Ketamine
Getting up-to-date on the research and practical application of psychedelic-assisted therapy is only half the story. Ketamine is a unique medicine in its bioactive properties for treating depression, but it can also produce a powerful psychedelic ...
Down the Rabbit Hole: The Mystical Side of Psychedelics – Keith Kurlander & Dr. Will Van Derveer – HPP145
In this episode, we explore the profound and often enigmatic nature of mystical experiences, particularly those induced by psychedelics. Through the lens of Western psychology and shamanic traditions, we examine encounters with mysterious entities...
Psychedelic Insights From One of the Earliest Researchers
For decades, Dr. Charles Grob has been researching applications of MDMA, psilocybin, and ayahuasca for a variety of human conditions including end of life anxiety, PTSD, depression, addiction, and more. His contributions have significantly shaped ...
Learning About Psychedelics from One of the First Pioneers
In our modern world, especially with the threat of COVID, there’s no question that the amount of people experiencing trauma and other related mental illnesses are exponentially rising. In treating these illnesses, prescribing specially developed m...
IPI Ketamine Medical Provider Online Training
Expand the spectrum of root causes of mental illness that you are equipped to resolve. Help your patients achieve genuine wellness with natural and pharmaceutical evidence-based practices.
Ketamine Psychotherapy: Treatment Resistant Depression By Will Van Derveer, MD
Getting proper training in Ketamine psychotherapy practice in order to help decide when patients might be appropriate for referral and to consider offering of Ketamine in the practice. Ketamine has been known to have low and tolerable risks with c...
Psychedelics for the Exploration of Self
The felt experience is the essence of being human. Psychedelic medicines are revolutionizing the mental health field, in part because they break down barriers of the psyche, opening up alternative avenues in perception. Altered states of conscious...
The Role of Spirituality In Psychedelic Therapy
The popularity of psychedelic therapy is on the rise as more individuals seek alternative and innovative approaches to mental health treatment. However, it is crucial that psychotherapists who offer psychedelic therapy have an understanding about ...
Psychedelics and Mindfulness
Both psychedelic use and mindfulness practices have been used for thousands of years across the world, often for spiritual purposes. While psychedelics are currently gaining therapeutic influence in the United States, mindfulness is still largely ...
The Best Ways to Stay Updated on the Latest Psychedelic News & Research
The field of psychedelic-assisted therapy is evolving rapidly, with new research, clinical trials, and policy changes emerging frequently. Whether you’re a practitioner, researcher, or enthusiast, keeping up with the latest findings is essential t...
The Brain's Way of Healing
Norman Doidge, MD
Noninvasive neuroplastic healing approaches for brain recovery.
How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence
Michael Pollan's exploration of the history and science of psychedelics. This book chronicles the resurgence of research into substances like psilocybin and LSD for treating mental health conditions.
Gaia
Premium streaming dedicated to consciousness, yoga, meditation, spirituality, and personal transformation.
Transcendental Meditation (TM)
The official website for the Transcendental Meditation technique. It provides information on the practice, its scientifically validated benefits for stress and anxiety, and how to find a certified TM teacher.
Why You Feel Lost in Life: Dr. Gabor Maté on Trauma & How to Heal
Why Normal Is a Myth-Dr. Gabor Maté
Closing the I: Research Takes a Closer Look at the Experience of Ego Dissolution
Steven Jay Lynn et al. / Binghamton University
Research exploring ego dissolution—the loss of ordinary sense of self—and its connection to psychedelics, meditation, and daily life experiences. Includes development of a validated scale to measure both positive (unity) and negative (ego loss) aspects of this phenomenon.
Ligare - A Christian Psychedelic Society
Ligare
A Christian psychedelic society discerning how faith and traditions may support the ethical and spiritually grounded use of psychedelics for healing and renewal. Ligare (Latin: 'to join or link') explores the intersection of Christianity and psychedelic-assisted therapy.
Authentic Relating Training International (ART)
An organization that teaches the practice of Authentic Relating, a set of skills for creating more meaningful and connected human relationships. They offer courses and workshops designed to improve communication and relational intelligence.
Super Mind
Exploration of mind and consciousness beyond ordinary understanding.
How to Change Your Mind (Official Trailer) | Netflix
The trailer for the Netflix docuseries based on Michael Pollan's book. It explores the history and science of psychedelics like LSD, psilocybin, MDMA, and mescaline for mental health.
Exploring Spirituality and Mental Health
McLean Hospital
How belief in higher power impacts acceptance and mental health.
The Mystical Experience Questionnaire (MEQ30)
An article providing the 30 questions of the Mystical Experience Questionnaire (MEQ30), a tool used in psychedelic research to measure the intensity of mystical-type experiences. These experiences are often correlated with positive therapeutic outcomes.
Johns Hopkins Center for Psychedelic and Consciousness Research
A leading academic center for advancing the understanding of psychedelics and consciousness. Their website provides information on their groundbreaking research, publications, and team of scientists.
Silver Hill Hospital
A non-profit psychiatric hospital in New Canaan, CT, offering comprehensive treatment for psychiatric and substance use disorders. They have a reputation for high-quality care and offer a range of programs, including a ketamine treatment program.
NAMI
National Alliance on Mental Illness - nation's largest grassroots mental health organization.
How to Integrate Your Shadow
Academy of Ideas
A resource focused on shadow. recommended as a valuable resource. by academy of ideas.
Can Psychedelics Trigger Psychosis?
Erica Zelfand
Clinical article examining the relationship between psychedelic use and psychotic episodes, including risk factors and harm reduction (2019).
The Elephant in the Room: Psychedelics and Social Justice
Charlotte Barton
MAPS Bulletin article addressing racial justice and equity issues in the psychedelic research and therapy community (2017).
Institute of Noetic Sciences (IONS)
Institute of Noetic Sciences
A nonprofit scientific research center founded in 1973 by Apollo 14 astronaut Dr. Edgar Mitchell, specializing in the intersection of science and profound human experience. IONS conducts research on consciousness, interconnectedness, and human potential.
My Therapy Session with Dr. Gabor Maté
Neuroscientist Explains WHY He Believes In GOD (How Prayer Works)
The Science of Gratitude & How to Build a Gratitude Practice | Huberman Lab Essentials
The Future of Psychedelic-Assisted Psychotherapy
Rick Doblin, PhD (TED, 2019)
TED talk by the MAPS founder explaining how MDMA-assisted therapy research works and what regulated medical use could look like.
Can Magic Mushrooms Unlock Depression? | Rosalind Watts | TEDxOxford
Rosalind Watts, PhD (clinical psychologist, Imperial College)
The clinical lead of Imperial College's psilocybin depression trial shares what patients taught her about how the treatment and its integration work.
The Real Risks of Psychedelics, Explained by an Expert
Matthew Johnson, PhD (Johns Hopkins) / Big Think
A leading Johns Hopkins researcher gives a candid, evidence-based account of the genuine psychological and medical risks of psychedelics.
Psychedelics and Other Unconventional Therapies | 60 Minutes Full Episodes
60 Minutes / CBS News (Anderson Cooper)
Mainstream 60 Minutes reporting on Johns Hopkins psilocybin trials, with researchers and trial participants describing the studies firsthand.
Psychedelic-Assisted Psychotherapy for PTSD — Rachel Yehuda, PhD
Rachel Yehuda, PhD (Icahn School of Medicine at Mount Sinai)
A pioneering trauma neuroscientist traces her path from skeptic to clinical researcher of MDMA-assisted therapy for PTSD in this Mount Sinai lecture.
The Science of Psychedelics for Mental Health | Dr. Robin Carhart-Harris
Robin Carhart-Harris, PhD (UCSF) on Huberman Lab
In-depth conversation with one of the field's most cited scientists on how psilocybin and related compounds act on the brain and what clinical trials show.
The Enneagram & Psychedelic Therapy (The Meaning Project, Ep. 194)
Daniel A. Franz, PhD
A conversation on personality frameworks and psychedelic-assisted healing from a clinician certified in psychedelic-assisted psychotherapy.
This Is Your Mind on Plants
Michael Pollan (journalist, UC Berkeley BCSP co-founder)
Pollan's follow-up to How to Change Your Mind examines opium, caffeine, and mescaline to explore how culture and law shape our relationship with psychoactive plants.
Good Chemistry: The Science of Connection, from Soul to Psychedelics
Julie Holland, MD (psychiatrist)
A psychiatrist explains the neurochemistry of human connection and how psychedelic research relates to attachment, oxytocin, and healing.
Psychedelics: The Revolutionary Drugs That Could Change Your Life — A Guide from the Expert
David Nutt, DM FRCP FRCPsych (Imperial College London)
A 2024 evidence-based overview from Imperial College's professor of neuropsychopharmacology covering what current research does and does not show about psychedelic medicine.
Psychedelic Integration: Psychotherapy for Non-Ordinary States of Consciousness
Marc Aixalà, MSc (psychologist, ICEERS); foreword by José Carlos Bouso, PhD
A clinician's guide to the theory and practice of integration psychotherapy for people processing non-ordinary states of consciousness.
The MAPS Podcast
Multidisciplinary Association for Psychedelic Studies
Official MAPS podcast featuring lectures and interviews with researchers working on psychedelic-assisted therapy science and policy.
Psychedelics Today
Joe Moore & Kyle Buller, MS (hosts)
Long-running education podcast interviewing researchers and clinicians about psychedelic science, ethics, integration, and policy developments.
Imperial College London Centre for Psychedelic Research
Robin Carhart-Harris, PhD (founding head); David Nutt, DM FRCP
The world's first university center dedicated to psychedelic science, publishing brain-imaging studies and clinical trials of psilocybin for depression.
NYU Langone Center for Psychedelic Medicine
Stephen Ross, MD; Michael Bogenschutz, MD
Academic medical center program running clinical trials of psilocybin for alcohol use disorder, cancer-related distress, and other conditions.
UC Berkeley Center for the Science of Psychedelics (BCSP)
Michael Pollan (co-founder); UC Berkeley faculty
University research center studying psychedelics through neuroscience, training, and public education, co-founded by journalist Michael Pollan.
Fluence — Psychedelic Integration Training for Clinicians
Ingmar Gorman, PhD & Elizabeth Nielson, PhD
Continuing-education organization founded by two clinical psychologists that trains licensed therapists in psychedelic integration and harm reduction.
Zendo Project — Psychedelic Peer Support Education
Zendo Project (founded by MAPS)
Harm-reduction education nonprofit that teaches evidence-based peer support principles for people experiencing difficult psychedelic experiences.
Oregon Psilocybin Services — Oregon Health Authority
Oregon Health Authority (state agency)
Official state page explaining how Oregon licenses and regulates supervised psilocybin services under Measure 109, the first program of its kind in the U.S.
Colorado Department of Natural Medicine
State of Colorado (regulatory agency)
Official Colorado state agency page describing the regulated natural medicine program created by the 2022 Natural Medicine Health Act.
Usona Institute
Usona Institute (nonprofit medical research organization)
Nonprofit research organization conducting FDA-regulated Phase 3 clinical trials of psilocybin for major depressive disorder.
The Microdose — News from the UC Berkeley Center for the Science of Psychedelics
UC Berkeley BCSP (journalism initiative)
Free journalism newsletter from UC Berkeley's psychedelics center covering research findings, FDA developments, and state policy news.
Psychedelic and Dissociative Drugs — National Institute on Drug Abuse
NIDA / National Institutes of Health
Federal research agency's plain-language overview of what science currently shows about psychedelic and dissociative drugs, including risks and open questions.
ACER Integration
Rosalind Watts, PhD (clinical psychologist, formerly Imperial College)
Integration framework and community developed by the former clinical lead of Imperial College's psilocybin depression trials, focused on connectedness before and after non-ordinary experiences.
Fireside Project — Psychedelic Peer Support Line
Fireside Project (nonprofit)
Free, confidential phone and text support line staffed by trained volunteers for people processing past or present psychedelic experiences.
FDA Draft Guidance: Psychedelic Drugs — Considerations for Clinical Investigations
U.S. Food and Drug Administration
The FDA's first formal guidance document for researchers on how to design scientifically sound clinical trials of psychedelic compounds.
FDA Rejects MDMA, Disappointing Drugmaker Lykos and Psychedelics Industry
NPR Shots (health news)
NPR's reporting on the FDA's 2024 decision requiring further study before MDMA-assisted therapy for PTSD can be approved, a key regulatory milestone.
MDMA-Assisted Therapy for Severe PTSD: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study
Jennifer Mitchell, PhD; Rick Doblin, PhD; et al. (Nature Medicine, 2021)
Open-access Phase 3 trial in Nature Medicine showing that MDMA-assisted therapy significantly reduced severe PTSD symptoms compared with therapy plus placebo.
Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo for Alcohol Use Disorder
Michael Bogenschutz, MD; Stephen Ross, MD; et al. (JAMA Psychiatry, 2022)
NYU randomized clinical trial finding that psilocybin paired with psychotherapy reduced heavy drinking days in adults with alcohol use disorder.
Psilocybin Produces Substantial and Sustained Decreases in Depression and Anxiety in Patients with Life-Threatening Cancer
Roland Griffiths, PhD; Matthew Johnson, PhD; et al. (Journal of Psychopharmacology, 2016)
Landmark Johns Hopkins randomized trial showing a single guided psilocybin session produced lasting relief of depression and anxiety in cancer patients.
Rapid and Sustained Symptom Reduction Following Psilocybin Treatment for Anxiety and Depression in Patients with Life-Threatening Cancer
Stephen Ross, MD; et al., NYU Langone (Journal of Psychopharmacology, 2016)
NYU's companion randomized trial documenting rapid and durable reductions in cancer-related anxiety and depression after a single psilocybin session with psychotherapy.
Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial
Charles Raison, MD; et al. (JAMA, 2023)
Recent multicenter randomized trial in JAMA showing a single dose of psilocybin with psychological support reduced major depression symptoms over six weeks.
Psychedelic Harm Reduction and Integration: A Transtheoretical Model for Clinical Practice
Ingmar Gorman, PhD; Elizabeth Nielson, PhD; et al. (Frontiers in Psychology, 2021)
Open-access clinical framework explaining how licensed therapists can legally and ethically support clients before and after psychedelic experiences without providing substances.
The Science of Pscilocybin and Its Use to Relieve Suffering
Roland Griffiths, Ph.D.
A resource focused on psychadelic research. highly recommended for its valuable insights and content. by roland griffiths, ph.d.
Inclusion of people of color in psychedelic-assisted psychotherapy: A review of the literature
Tiffany I. Michaels et al.
BMC Psychiatry systematic review examining barriers to inclusion and strategies for increasing diversity in psychedelic research (2018).
Multidisciplinary Association for Psychedelic Studies (MAPS)
Rick Doblin, PhD (founder)
Nonprofit research and education organization that has sponsored FDA-regulated clinical trials of MDMA-assisted therapy for PTSD since 1986.
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